Multicentre randomised controlled trial confirms the significant benefits of Phagenyx® treatment for tracheostomised stroke patients with dysphagia

University of Manchester spin-out, Phagenesis Ltd, a pioneering leader in the treatment of dysphagia, is pleased to announce today the publication of its most recent randomised controlled trial (PHAST-TRAC) in the journal Lancet Neurology read more.

Reinhard Krickl, CEO of Phagenesis, said: “The publication of the excellent PHAST-TRAC results in such a well-positioned peer-reviewed journal is a big achievement for Phagenesis. It emphasises the high clinical relevance of the benefits of Phagenyx treatment as demonstrated in the trial, addressing a genuine unmet medical need.

Around 12.5% of all stroke patients admitted to hospitals undergo mechanical ventilation and 16.3% of them receive a tracheostomy.1  Safe removal of the tracheostomy cannula is a major goal in the rehabilitation of tracheostomised patients to reduce the risk of respiratory complications, death and duration of hospitalisation.1-3 However, swallowing problems substantially delay the removal of the tube after breathing has stabilised.2,4-5

Oern Stuge, MD, Chairman of Phagenesis, stated: “These patients don’t have access to an efficient treatment that addresses the underlying neurological cause of dysphagia. With the company’s technology, we can help many patients by improving their outcomes whilst reducing the risks and costs that come with this condition.” 

The PHAST-TRAC results confirm that tracheostomised stroke patients with swallowing problems can benefit from treatment with Pharyngeal Electrical Stimulation (PES), a novel therapy based on ground-breaking research. Tracheostomy decannulation (removal of cannula) was achieved safely in 49% of patients from the PES group vs 9% in the control groupMoreover, patients who responded to PES treatment had an average reduction in hospital length of stay of 22 days.6

The North of England Life Sciences Accelerator: application now open

The North of England Life Sciences Accelerator (NELSA) is looking for early stage businesses & those with a business idea in the life science and healthcare sector.

An integrated programme of support, NELSA is a unique collaboration between the BioCity Group, BioHub at Alderley Park, Alderley Park, The N8 Research Partnership, the Northern Health Science Alliance, Alderley Park Ventures and Catapult Ventures.

Successful applicants will be invited to join NELSA and benefit from:

*        A place on the BioCity Accelerator programme

*        Seed funding via Catapult Ventures & Alderley Park Ventures

*        1:1 coaching

*        Mentorship via the UK wide Expert Network

*        Access to clinicians / clinical validation via the NHSA

*        Advice & introductions to investors to secure further funding

*        Free virtual tenancy at BioHub at Alderley Park

*        Access to shared facilities & analytical laboratory at Alderley Park

Application deadline: 17th September 2018

To apply or find out more about NELSA, please visit

Clive Rowland appointed as Associate Vice-President for Intellectual Property

CEO of UMI3 Ltd assumes Associate Vice-President role.

Clive Rowland has been appointed as the University’s Associate Vice-President for Intellectual Property (IP) Matters. The new role will take effect in January 2019.

Clive will step down as Chief Executive Officer (CEO) of UMI3 Ltd (The University of Manchester Inspire, Invent, Innovate Ltd) following the appointment of a new CEO, the search for which has already begun.

This new post recognises the importance of IP to the University.

The Associate Vice-President role will be part-time and Clive will work closely with Professor Luke Georghiou, Deputy President and Deputy Vice-Chancellor, and other senior colleagues, to inform and advise on IP policy, IP good practice and benchmarking; IP aspects of strategic alliances and contracts; and Clive will also act as an IP ambassador for the University.

Clive co-founded, and was at the helm of, one of the UK’s earliest formed university commercialisation companies (UMIST Ventures Limited) which was established in 1988. Clive has led and evolved UMI3 since its formation in 2004 to become one of Europe’s leading university technology transfer organisations.

Over the years Clive has been active in numerous successful commercial transactions; presented at key international spin-out and licensing conferences; acted as an expert contributor on university IP to national committees and inquiries; and been a board and committee member of relevant professional networks and associations such as the British Venture Capital Association.

A Fellow of the Institute of Directors and of the Chartered Institute of Marketing, he received the Italian Order of Merit for services in promoting Manchester’s business relations with Italy.


Inaugural UMIP Innovation Award winners revealed

Award winners and judges

SkinBioTherapeutics Ltd, a life science company focused on skin health, landed Leading Spin-Out while Ian and Lynne Hampson, both molecular virologists, came out on top in the Commercial Licence category for their work on novel uses of lopinavir and ritonavir in HPV related cancers.

The Digital Innovation prize went to John Morley of PhraseBank which offers a downloadable phraseology resource to help researchers of all abilities improve their academic writing and Cable Coatings was named as the most Successful Start-up. Application of spectrally optimised coatings to the outside of aerial cables to boost grid capacity in a durable, easy to apply, cost-effective way.

Professor Cath O’Neill, the chief executive of skin health company SkinBioTherapeutics, was also revealed as Innovation Champion during the awards ceremony which took place at The University of Manchester’s Innovation Centre, UMIC. Cath has found new ways of promoting and maintaining skin health and combating chronic skin diseases. Her second spinout SkinBioTherapeutics PLC was admitted the AIM market in 2017 and the placing raised £4.7m (gross). Cath acts as a champion for business engagement in FBMH and was named as one of the top 50 female leaders in healthcare business in the UK.

UMIP Director of Operations Dr Rich Ferrie paid tribute to all the innovators shortlisted.

He said: “In the past we’ve always nominated our innovators for regional awards. This year we wanted to recognise their hard work and excellence internally so created the UMIP Innovation Awards 2018.

“And we’re delighted that we held this inaugural event as it was a very positive endorsement and a real opportunity to showcase the breadth of science that we have in this University.”

He added: “Each who made the shortlist deserved their place and I know from speaking with the judges just how hard it was to pick overall winners in the five categories.

“Commercialising science isn’t an easy process. The commitment that these individuals who to fit commercialising their science around research, teaching, administration roles and clinical duties is quite something.

“They should be commended for their hard work and I hope their journeys are successful ones from here on in.”

Please see video interviews with the winners here




UMIP Innovation Optimiser Celebrates Success at the IO Showcase 2018

Over 100 entrepreneurs, colleagues from The University of Manchester and wider support partners gathered at the Showcase to hear how the UMIP Innovation Optimiser (IO) has supported and nurtured new businesses coming out of the University.

2018 sees another eight IO supported University of Manchester Start-Ups begin their journey including- Dataviewer Ltd, Sleeping Lions Adventures Ltd, The Pentone Family Ltd, Neurolytics Ltd, IMPACT CIC, Macawly Ltd, Third Floor Systems Ltd and PABBS Ltd. This brings the total to have graduated through the UMIP Innovation Optimiser programme to over 20 within three years.

IO Director, Tony Walker revealed that over £265,000 worth of support and awards have been provided by the IO in less than three years while 164 entrepreneurs from across The University of Manchester campus have engaged in the programme.

Professor Luke Georghiou, Deputy President and Deputy Vice-Chancellor at The University of Manchester, emphasised the importance of supporting staff, academics and research students who may have an idea for a commercial start-up or social enterprise.

Speaking after IO Showcase –Tony said: “IO was launched just over two-and-a-half years ago and is proving to be a huge success boosting the Manchester start-up scene”

“It provides a vibrant and supportive environment for individuals or teams with an idea, innovation or venture in which they are empowered to develop and build their business.”

He added: “The IO Showcase 2018 very much highlighted some of the fantastic businesses and innovations being developed by staff, academics and research students at The University of Manchester.

“It’s now about IO going from strength to strength and building on the partnerships we have created including with Business Growth Hub, dwf, Manchester Enterprise Centre, TiE Global and many more, and continuing to engage with active entrepreneurs across the campus who we may be able to support through our Ignition, Roadmap, Momentum and Spotlight programmes.”

Dr Laura Etchells, UMIP Enterprise Development Manager said: “We were delighted to showcase a range of new and established entrepreneurs today including ESOL Stepping Stones, Bundlee Ltd and UrbanChain Ltd, all eager to inspire and motivate tomorrow’s innovators.”

IO, which provides support for aspiring entrepreneurs wishing to develop start-up businesses, social ventures and research student enterprises, through educational resources and agile mentoring, was developed by UMIP to complement its renowned Intellectual Property (IP) commercialisation activity.

Since its inception IO has held 62 events and engaged with more than 1,300 people in outreach activities across the University campus.

Ellie Buckley, UMIP Enterprise Development Executive and event organiser said: “Our second Showcase was attended by more than 100 people and the feedback has been incredible.

“This event is a fantastic opportunity for our entrepreneurs to share their stories, connect across campus and network with the wider enterprise community in Greater Manchester. We’re looking forward to the next 12 months at IO.”

The IO Showcase 2018 was held on Thursday 26th July at The University of Manchester Innovation Centre on Grafton Street.

To find out more, contact one of the Innovation Optimiser team:

Ellie Buckley, Enterprise Development Executive  or 0161 606 7265

Laura Etchells, Enterprise Development Manager or 0161 606 7264

Tony Walker, Director of Innovation Optimiser, or 0161 603 7780



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